5 Portrait Cards

10 Blue Cell Component Cards

10 Green Cell Component Cards

10 Red Cell Component Cards

30 Special Cards

15 Wild Cards

30 Green Miniature Microscopes

20 Yellow Miniature Microscopes

15 Pink Miniature Microscopes

1 Red Miniature Trophy

4 Blue Miniature Trophies

12 Dices

5 Character Game Pawns

1 Start Hexagon Platform

1 Finish Hexagon Platform

1 Trail Board

1 Plant Cell Board Cutout

1 Animal Cell Board Cutout

1 Bacterial Cell Board Cutout

1 Cell Of Wonders Booklet

1. Select your favored character or randomly draw a Portrait Card to decide which character you will play. Featured Scientists: Robert Hooke (1635-1703); Antonie van Leeuwenhoek (1632-1723); Matthias Jakob Schleiden (1804-1881); Theodor Schwann (1810-1862); and Rudolf Carl Virchow (1821-1902).

2. Each player must be given time to introduce their characters by reading the information already provided in the Portrait Cards — highlighting the knowledge about cells from the discoveries of numerous scientists; these sets of cards are accompanied by a character game piece for each scientist featured, respectively. 

3. Give each player a set of random Power Cards according to the chart below. Don’t be too discouraged by the number of cards you have, since each player will be given a chance to take plenty more Power Cards within the tiles. It is an unknown, interesting, and unpredictable card that represents how cells take in nutrients, convert these nutrients into energy, carry out specialized functions, and reproduce as necessary. The various subtypes of Power Cards that players can take or draw in the game are classified into two kinds: the wild cards and the special cards.

                                                            Number of Players             Number of Power Cards

                                                                      2 Players                                    5 Cards

                                                                      3 Players                                    4 Cards

                                                                      4 Players                                    3 Cards

                                                                      5 Players                                    2 Cards

4. Now, all players must roll their dice. The sum of the dice will determine each player's turn from increasing to descending hierarchy, to move forward along the board. One with the highest sum of dice will be the first player to take their turn, and then the play continues in the mentioned order. Otherwise, the play moves to the next person from right to left or vice versa. 

5. Each turn, a player must place their character game pawns on the board and then immediately take the action required in the tile in order to collect resources such as various Cell Component Cards and miniature microscope supplies. Strictly, no more than one should be positioned on the same tiles. The first one in that position shall remain and the last one must move back one tile. 

6. Shuffle the Cell Component Cards. A player draws a Closer Look Card — containing straightforward trivial and important information about a certain part's structure, organelles, function, and theory. These cards also indicate points and ‘read it aloud’ instructions. After taking the actions required by this card, players must place this card in the corresponding part of any of the three cell types positioned within the board. This furthermore makes a puzzle recognition on the board; the player must only accumulate the exact number of microscopes indicated in that particular card.

7. Points converted in the form of microscopes shall be only accumulated when a certain card instructs so. Again, these can only be found in the Closer Look Cards. The colors of microscopes vary according to each featured microscope kind and players can take a hint as to how many points ought to be accumulated: (a) Light Microscope (LM) – a green microscope equivalent to 5 points each. (b) Transmission Electron Microscope (TEM) – a yellow microscope equivalent to 10 points each; (c) Scanning Electron Microscope (SEM) – a pink microscope equivalent to 15 points each.

8. Players must also read the information aloud for every player to hear as instructed in the Closer Look Cards.

9. After collecting the points, take notice of a certain part of the cell featured, which can still be found in the Closer Look Cards, a player must then place it on top of the cutout boards to complete a puzzle-like diagram until the very end of the game. 

10. Once a player decides to use any of the Power Cards in his/her supply, he/she must make sure that he understands the instructions already provided in the card; players can take a hint as to when exactly the card could be used. If unsure, players may always open the booklet "Cell Of Wonders" and read the mechanics containing CytoSOFT's Game Play and Set Up.

11. While racing to the finish line, players can make total use of their resources. 

12. Each player's turn depends on the sum of their rolled dice, furthermore, rounds can always be refreshed only until resources run out. Keep rolling the dice and be very careful in moving.

13. If there are no more randomized Closer Look Cards or Power Cards to be drawn, players must either continue rolling their dice to the finish line until someone is considered a winner or give up all their resources to refresh the game, while their positions in the tiles are retained. 

14. Once a player gets to the finish platform, he/she is immediately considered the winner, and runner-ups will be determined by how close they were to the tail end of the board. 

15. The winner will receive an "Outstanding Young Biologist Award", a red miniature trophy, whereas runners-up will receive a "Young Biologist Award" marked by a piece of blue miniature trophy.